Calprotectin is the inflammatory protein that can be measured in the stool. A calprotectin level below 60 is considered normal.
If the calprotectin level is 150 or higher, significant inflammation is present in the body. It needs to be checked out further with a colonoscopy and an assessment by a gastrointestinal specialist. Some of the conditions that can cause high levels of calprotectin include inflammatory bowel disease, certain medications such as non-steroidal anti-inflammatories (NSAIDS). High blood pressure can also elevate calprotectin levels. Remember to get your blood pressure checked if your calprotectin levels are high.
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Get blood and stool tests to check for the levels of other inflammatory markers such as lysozyme and c-reactive protein. These and other additional tests can help distinguish between irritable bowel syndrome and inflammatory bowel disease.
- https://www.ncbi.nlm.nih.gov/pubmed/31680263
- https://www.ncbi.nlm.nih.gov/pubmed/27147826
- https://www.ncbi.nlm.nih.gov/pubmed/30953184
